I read some said that could be a factor? Hope you get some answers soon. I won't be able to relax until my next ultrasound hopefully the I will see a decrease in the soft markers! I will keep you all informed about this issue. Has someone fallen into such situation? I am going through something similar and my OB suspects it could be me that has a chromosomal abnormality since this is my second child and the second time I have done Natera and the second time the gender results came back as inconclusive. Non-invasive prenatal testing (NIPT) using cell-free DNA in maternal blood is a relatively new screening modality for the common trisomies of chromosomes 21, 18 and 13 and sex chromosome aneuploidies. Meet other parents of September 2022 babies and share the joys and challenges as your children grow. I am definitely going to try to stay away from google. . Defining the genetic relationship between people or tissue samples using DNA markers. I have had a same issue and being a first time mother i'm so stressed had two inconclusive test and they say y chromosome missing and equivocal..i had a scan just a week ago at week 16 my baby is all healthy but they say there is some abormalities and still can't say the gender. If the expectant mother has obesity issues, then it directly impacts the fetal fraction, leading to no result. Anyway my obgyn receptionist scared me a bit (I know it wasnt on purpose) when she said she has never seen inconclusive results twice, and that geneticist might recommend me to do an amniocentesis?? I believe she had it done only twice. I think in my case, my first test must have been borderline. Anyone else have this come up? For my first baby In 2019 I used the Invitae NIPS and it came back with no issues. I just got referred to McMaster as well with a high risk FTS scan/blood work. Your post will be hidden and deleted by moderators. 20062023 BabyCenter, LLC, a Ziff Davis company. What the heck, now so stressed! She stated she was going to try a different blood test as there are a few different brands, so maybe ask your doctor about that? Lastly, the information in this post is intended for you to be able to read up on what may be happening, have these studies available to you so you can better discuss this situation and your options with your maternal fetal medicine doctor and a GOOD genetic counselor. No NIPT test is accurate below 3.5%. I wouldn't necessarily do the amnio for that if the baby is otherwise healthy. Learn more about, Twins & Multiples: Your Tentative Time Table. Just tonight I found out the second draw of blood for the Harmony test came back inconclusive. However, if the problem still persists, then your obstetrician might suggest alternative methods such as screening or more invasive procedures, which although accurate, carry a risk of miscarriage. Archived discussions are usually a bit older and not as active as other community content. 3) anything that the NT scan would show (that NIPT wouldnt), the anatomy scan will also show in 20 weeks and that is a standard test for AMA people, as well. my reason for doing the NIPT was similar to yours, haha. The inconclusive result was due to my fetal fraction being 4.4%. Both of these usually go away but I'm just worried! You are right! your gp will sort it out for you love. This was simply a technical issue within the laboratory. The #1 app for tracking pregnancy and baby growth. No, NIPT is a screening test, not a diagnostic test. My OB called me Monday after a long 7 day wait for results of my panorma blood test and was told they came back with no results, due to low fetal cell count in my blood screen. All rights reserved. As always, take any information given here and online for what it is - information - and always discuss further treatment plans with your physicians, however with caution. This time they were able. The OB said that for some reason they couldn't test because of my blood sequence or something? Hope you're doing OK. Ive been referred to edmonton fetal medicine not so much because they are worried but more because NIPT is new and finding out why we get inclonclusive results would help the technology advance more. Since the nIPT is inconclusive youll have this redrawn but in the mean time I would get the triple screen. No, I am a public patient. Thus, if you received no result during your non-invasive prenatal paternity test, then it might be best to check if any of these 3 factors might be in play. Try not to worry! The NIPT shows that I am high risk for Turner Syndrome with my baby girl. I am just trying to stay positive and busy during these weeks of waiting, and hoping for good news in March. Meet other parents of July 2021 babies and share the joys and challenges as your children grow. Of course, this can be dispelled with subsequent retests. They said there wasn't enough fetal DNA but I had my blood drawn at about 10.5 weeks and then 12 weeks and it was still inconclusive! Canceled due to too many follicles (10 + that were large); BENCHED. Noninvasive prenatal tests, or NIPTs, screen for an array of rare genetic conditions. That only happens in 1% of tests. In some cases, they will flag a. A failed test result will only be reported after testing of both samples) Inconclusive result. Patients having this testing should know that NIPT results do not diagnose a genetic condition or give a yes/no answer, and should seek follow-up testing if appropriate. The #1 app for tracking pregnancy and baby growth. This educational content is not medical or diagnostic advice. Then 12 week scan showed 3mm NT. I wish you and your baby boy all the best too! It can come with its own set of risks. Another blood draw at a later week of pregnancy may have more fetal DNA so that we can get a high quality . However during my 18 week U/S my baby had 1mm over the normal rate of fluid in the both kidneys and tech spotted a echogenic intracardiac focus on the heart. Research suggests that about 5 percent of women get no result at all. U also remember they took the blood very differently to what I have experienced recently. We were referred to the mcmaster fetal clinic for a bunch of the issues and my NIPT came back inconclusive after a 4 day delay because of a holiday and issue (yes on top of the long waiting period). My nipt/panorama/harmony results came back inconclusive both times. 16 week ultrasound scheduled for Monday, June 6 and Amniocentesis scheduled for Wednesday, June 8. Get weekly updates on baby and your body. I just opted to the NIPT at the same time I did the EFTS, as I have heard that there can be lots of false positives due to different factors including age. I met with a genetic counsellor who reviewed my file, age and risk, nd we decided together no further testing was needdd however for peace of mind and funsies we did the quad test which is a hormone test and can flag for trisonmies. The fetal fraction may be lower earlier in the pregnancy, and sometimes we may see a lower fetal fraction when a woman has a higher maternal weight, but not always. 2005-2023Everyday Health, Inc., a Ziff Davis company. 2005-2023Everyday Health, Inc., a Ziff Davis company. I really do feel for those that don't have as many affordable options. Symptmes de grossesse ne jamais ignorer, Moyens naturels pour dclencher l'accouchement. 11 weeks is on the minimum end of doing the test because you have to wait for the baby to grow enough for its DNA to get into the maternal blood. Your test result shows that your pregnancy is at low risk for these three conditions. I would DEFINITELY choose the NIPT test. you will see them all over the place here. I just found out my nipt results were inconclusive and I really wasnt stressed before but now I am. Both said due to low fetal DNA at 2.6% and 2.7% respectively. Update: I did the redraw and got my results back yesterday. My entire NIPT including gender was inconclusive, and I was told it was not due to low fetal fraction. Thanks for sharing your story! Had my harmony test at 10 weeks 3 days. All rights reserved. It has to be at least above 4 percent to give a conclusive result. Prediction of other SCA was more accurate. Note that once you confirm, this action cannot be undone. 2) NIPT tests are more accurate and test for MORE genetic disorders (they also tell you sex, if you want to know). The main purpose of NIPT is to screen for major chromosome conditions (Down syndrome, trisomy 18, and trisomy 13). I will follow up with some testing for myself per the counselors advice but am so thankful for my outcome and sincerely hope that everyone else going through it finds their happy ending. Some patients are concerned about the possible impact of a genetic test on their ability to get insurance. Just waiting for the office to call back to rebook. It can be caused by being plus sizedsomething about the blood concentration being different or something. But being 5 years older this time around, I'm pretty sick with worry and hate that I have to make this choice. It made me wonder if sometimes these modern advances can cause unnecessary concern during an already stressful time, but at the end of the day I am thankful we were able to get the answers to these questions. I don't think i would want to do an amnio either as I am not even high risk. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Did you get a conclusive test result in the end? That means whatever caused no result the first time is still interfering with the test. yesteray on my 16 weeks scan they tell me it looks like a girl! Went back yesterday and did a redraw, and now I'm hoping this one takes. And what was your BMI? No problems and the procedure was not nearly as bad as I thought. I appreciate those who chime in as we all remember how difficult to be in this situation. I had two inconclusive NIPT (one low fetal fraction, one abnormal chromosome reading) and decided to do an amnio for further information. So, a "normal" NIPT result doesn't guarantee a healthy baby, and an "abnormal" result doesn't mean your baby definitely has a certain condition. Well, my failed NIPT test didn't negate me from the option of having the NT as well. I just found out today at 12.5 weeks that my test was not conclusive. the test and lead to no result. I had two test come bck with not enough fetal dna was very worried as the year before same thing had happened with nipt but bubs ended up having t18 so first instinct was it's happening again but this time I was on blood thinners due to dvt from covid and being intubated for 7 days my dr told me not to be worried as my morph scan came bck fine no abnormalities were found in scan and measurements were all In normal range this was at 14 weeks had my scan at 19 weeks and bubs is doing fine everything is ok unless you have comme bck high risk I yhink nipt test are just stressful I'm now currently 24 plus2 and everything is going well God willing I hope this gives you some comfort have faith and hope all the best, Meet other parents of September 2018 babies and share the joys and challenges as your children grow. The Sonic Genetics website includes general information regarding genetic testing, as well as specific information about particular tests. I'll do my 3rd test at nearly 16 weeks. Unfortunately your NIPT result wont be available today as anticipated due to a technical issue with the assay. What company did your test? We keep them up because there are a ton of great conversations here and we believe you deserve to see them all. During pregnancy, opting for a non-invasive prenatal test has become the norm. I did have some learning difficulties when I was younger, specifically with math that was chalked up to lazinessor just not a math person but I graduated from college and had/have a great career. Non-Invasive Prenatal Testing (NIPT) is a screening test that examines small fragments of DNA (cell free DNA (cfDNA) which are released from the placenta. Create an account or log in to participate. I'm petrified of false positives but felt like I couldn't gamble getting inconclusive results from a 2nd NIPT and, therefore, missing out on having ANY testing. To help you get started read our. this is why, 1) NT scans (look around) have TONS and TONS of false positives. 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